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| 名称： | anti- GAPDH antibody |
|---|---|
| 货号： | FNab03342 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格 ： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度 ： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原 ： | glyceraldehyde-3-phosphate dehydrogenase |
| 免疫原别称： | GAPD antibody, G3PD antibody, GAPDH antibody, OK/SW cl.12 antibody |
| 分子量 ： | 36 kDa |
| 验证应用： | ELISA, IHC, WB |
| 建议稀释比例： | WB: 1:1000-1:5000; IHC: 1:100-1:500 |
| UniProt ID： | P04406 |
| 克隆性 ： | 多克隆 |
| 背景介绍 ： | Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules(By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate(G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT(gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition i |
| 图像： |  Immunohistochemistry of paraffin-embedded human colon cancer using FNab03342(GAPDH antibody) at dilution of 1:100。  various lysates were subjected to SDS PAGE followed by western blot with FNab03342(GAPDH antibody) at dilution of 1:2000。 |
