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18062437365
名称: | anti- PCNA antibody |
---|---|
货号: | FNab06215 |
适应种属: | 人源,大鼠,小鼠 |
规格: | 100ug(微克) |
状态: | 液体 |
纯化方法: | 免疫亲和纯化 |
纯度: | 经SDS-PAGE分析,纯度大于95% |
宿主: | 兔 |
亚型: | lgG |
存储: | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融) |
免疫原: | proliferating cell nuclear antigen |
免疫原别称: | Proliferating cell nuclear antigen antibody, Cyclin antibody |
分子量: | 38 kDa |
验证应用: | ELISA, WB, IHC |
建议稀释比例: | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
UniProt ID: | P12004 |
克隆性: | 多克隆 |
背景介绍: | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
图像: | Immunohistochemistry of paraffin-embedded human stomach cancer using FNab06215(PCNA antibody) at dilution of 1:50。 A431 cells were subjected to SDS PAGE followed by western blot with FNab06215(PCNA antibody) at dilution of 1:1000。 |