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      发布时间:2023-08-30 16:39   咨询量:
    1. 英文名称 : anti- Chk1 antibody
    2. 产品货号: FNab01653
    3. 适应种属:人源,大鼠,小鼠
    4. 宿主 :小鼠
    5. 亚型: IgG2a
    6. 验证应用 : ELISA, WB, IHC
    7. 简介:js3333线路检测中心生物抗Chk1抗体经SDS-PAGE分析,纯度大于95%,采用蛋白A/G柱纯化方法,为用户提供高亲和力、高特异性的优质抗体。
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      产品详情
      名称: anti- Chk1 antibody
      货号 : FNab01653
      适应种属:人源,大鼠,小鼠
      规格 :100ug(微克)
      状态:液体
      纯化方法:蛋白A/G柱纯化
      纯度 :经SDS-PAGE分析,纯度大于95%
      宿主 :小鼠
      亚型 : IgG2a
      存储:用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融)
      免疫原: CHK1 checkpoint homolog
      免疫原别称: CHEK1 antibody, Chk1 antibody
      分子量 : 50 kDa
      验证应用 : ELISA, WB, IHC
      建议稀释比例: WB: 1:500-1:2000; IHC: 1:20-1:200
      UniProt ID: O14757
      克隆性:单克隆
      背景介绍 :HEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa.
      图像:Chk1抗体
      Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab01653(CHK1 Antibody) at dilution of 1:50。

           anti- Chk1 antibody
      HeLa cells were subjected to SDS PAGE followed by western blot with FNab01653(CHK1 Antibody) at dilution of 1:1000。

      

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