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产品详情
| 名称 ： | anti- P53 antibody |
|---|---|
| 货号： | FNab06083 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态 ： | 液体 |
| 纯化方法 ： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储 ： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | tumor protein p53 |
| 免疫原别称： | Antigen NY CO 13 antibody, Cellular tumor antigen p53 antibody, FLJ92943 antibody, LFS1 antibody, P53 antibody, Phosphoprotein p53 antibody, TP53 antibody, TRP53 antibody, tumor protein p53 antibody, Tumor suppressor p53 antibody |
| 分子量 ： | 53 kDa |
| 验证应用： | ELISA, WB, IHC, IF |
| 建议稀释比例： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100 |
| UniProt ID ： | P04637 |
| 克隆性： | 多克隆 |
| 背景介绍： | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
| 图像： |  Immunofluorescent analysis of HepG2 cells using FNab06083 (P53 Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L)。  Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab06083(P53 antibody) at dilution of 1:100。  MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06083(P53 antibody) at dilution of 1:1000。 |
