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产品详情
| 名称 ： | anti- RAD51 antibody |
|---|---|
| 货号 ： | FNab07079 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格 ： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法 ： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主 ： | 兔 |
| 亚型 ： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | RAD51 homolog |
| 免疫原别称 ： | RAD51A antibody, RECA antibody |
| 分子量 ： | 37 kDa |
| 验证应用： | ELISA, WB, IP,IHC |
| 建议稀释比例： | WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500 |
| UniProt ID ： | Q06609 |
| 克隆性： | 多克隆 |
| 背景介绍： | Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. |
| 图像： |  Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab07079(RAD51 Antibody) at dilution of 1:200。
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