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      抗RAB8A抗体

    1. 一抗
    2. 发布时间 :2023-09-05 15:17   咨询量 :
    3. 英文名称: anti- RAB8A antibody
    4. 产品货号: FNab07045
    5. 适应种属:人源,大鼠,小鼠
    6. 宿主 :兔
    7. 亚型 :lgG
    8. 验证应用: ELISA, WB, IF, IP
    9. 简介 :js3333线路检测中心生物抗RAB8A抗体经SDS-PAGE分析,纯度大于95%,采用免疫亲和纯化方法,为用户提供高亲和力、高特异性的优质抗体。
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      产品详情
      名称: anti- RAB8A antibody
      货号 : FNab07045
      适应种属:人源,大鼠,小鼠
      规格 :100ug(微克)
      状态:液体
      纯化方法:免疫亲和纯化
      纯度:经SDS-PAGE分析,纯度大于95%
      宿主 :
      亚型:lgG
      存储 :用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融)
      免疫原: RAB8A, member RAS oncogene family
      免疫原别称  : MEL antibody, Oncogene c mel antibody, RAB8 antibody, RAB8A antibody, Ras related protein Rab 8A antibody
      分子量: 24 kDa
      验证应用: ELISA, WB, IF, IP
      建议稀释比例 : WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100
      UniProt ID : P61006
      克隆性:多克隆
      背景介绍 :The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites(AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization. Plays an important role in ciliogenesis. Together with MICALL2, may also regulate adherens junction assembly. May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose
      图像:RAB8A抗体
      IP Result of anti-RAB8A (IP:FNab07045, 3ug; Detection:FNab07045 1:500) with HeLa cells lysate 2500ug。

           anti- RAB8A antibody
      HeLa cells were subjected to SDS PAGE followed by western blot with FNab07045(RAB8A antibody) at dilution of 1:1000。

      

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