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18062437365
名称: | anti- CD86 antibody |
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货号: | FNab01504 |
适应种属: | 人源,大鼠,小鼠 |
规格: | 100ug(微克) |
状态: | 液体 |
纯化方法: | 免疫亲和纯化 |
纯度: | 经DSD-PAGE分析,纯度大于95% |
宿主: | 兔 |
亚型: | lgG |
存储: | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融) |
免疫原: | CD86 molecule |
免疫原别称: | Activation B7 2 antigen antibody, B7 2 antibody, B70 antibody, BU63 antibody, CD28LG2 antibody, CD86 antibody, CD86 molecule antibody, CTLA 4 counter receptor B7.2 antibody, FUN 1 antibody, LAB72 antibody |
分子量: | 75 kDa |
验证应用: | ELISA, WB,IHC,IF |
建议稀释比例: | WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200 |
UniProt ID: | P42081 |
克隆性: | 多克隆 |
背景介绍: | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.(Microbial infection) Acts as a receptor for adenovirus subgroup B. |
图像: | Immunofluorescent analysis of RAW264.7 cells using FNab01504 ( CD86 Antibody) at dilution of 1:50。 Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01504(CD86 Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9)。 Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01504(CD86 antibody) at dilution of 1:500。 |