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18062437365
名称: | anti- Vimentin antibody |
---|---|
货号: | FNab09408 |
适应种属: | 人源 |
规格: | 100ug(微克) |
状态: | 液体 |
纯化方法: | 免疫亲和纯化 |
纯度: | 经SDS-PAGE分析,纯度大于95% |
宿主: | 兔 |
亚型: | lgG |
存储: | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融) |
免疫原: | vimentin |
免疫原别称: | FLJ36605 antibody, VIM antibody, Vimentin antibody |
分子量: | 55 kDa |
验证应用: | ELISA, WB, IHC, IF |
建议稀释比例: | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
UniProt ID: | P08670 |
克隆性: | 多克隆 |
背景介绍: | This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract. |
图像: | Immunofluorescent analysis of HepG2 cells, using FNab09408(VIM antibody) at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red)。 Immunohistochemistry of paraffin-embedded human tonsillitis using FNab09408(VIM antibody) at dilution of 1:50。 NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab09408(VIM antibody) at dilution of 1:1000。 |